| Wednesday, May 21, 2008 |
| 12:00 AM | Everybody Loves Raymond Episode: The Bigger Person Robert's attempt to play peacemaker backfires, escalating the Cold War between Marie and Debra |
| 12:30 AM | Paid Program |
| 01:00 AM | Family Guy Episode: The Thin White Line Brian becomes the top dog at a local police department where his nose gets him into trouble. Voices of Seth MacFarlane, Alex Borstein, Seth Green and Mila Kunis. Guest voices: Haley Joel Osment, Patrick Warburton and Leif Garrett |
| 01:30 AM | Will & Grace Episode: Back Up Dancer Jack wangles his way into Janet Jackson's (guest starring as herself) performance tour as a backup dancer |
| 02:00 AM | The Bernie Mac Show Episode: My Privacy Bernie realizes Bryana and Jordan are too old to share a room, so he moves her in with Vanessa, who is less than thrilled |
| 02:30 AM | My Wife and Kids Episode: Poker Face Michael tells Jr. to spend some time away from Vanessa and the baby, but his advice backfires |
| 03:00 AM | That '70s Show Episode: It's a Wonderful Life An angel (guest star Wayne Knight) attempts to cheer up a heavy-hearted Eric (Topher Grace) by transporting him to the 1980s and showing him how his friends' lives turn out |
| 03:30 AM | Sex and the City Episode: The Good Fight Living with Aidan suffocates Carrie; Samantha grows closer to Richard; Miranda wonders if pregnancy precludes sex |
| 04:00 AM | The Bernie Mac Show Episode: Carfool Carpool complications wreck Bernie; a boy in the carpool starts blackmailing Jordan to be his friend, and the boy's father won't stop bothering Bernie |
| 04:30 AM | King of the Hill Episode: Four Wave Intersection When Hank takes Bobby, Joseph and Connie to a water park, a group of surfer bullies approaches them; Bill becomes known throughout Arlen as the ``Heat-Waver.'' |
| 05:00 AM | Shepherd's Chapel |
| 06:00 AM | Malcolm in the Middle Episode: Humilithon Malcolm's parents destroy his dream of being popular on his very first day of school |
| 06:30 AM | Paid Program |
| 07:00 AM | Good Morning West Virginia |
| 08:00 AM | Sherlock Holmes in the 22nd Century Episode: The Fall and Rise of Sherlock Holmes Lestrade and Holmes try to track a villain |
| 08:30 AM | Paid Program |
| 09:00 AM | Paid Program |
| 09:30 AM | Paid Program |
| 10:00 AM | Family Feud Teams compete to match answers of nationwide surveys |
| 10:30 AM | Family Feud Teams compete to match answers of nationwide surveys |
| 11:00 AM | Judge Hatchett A troubled teen learns to use graffiti for art instead of vandalism |
| 11:30 AM | Judge Hatchett A woman seeks to prove her ex-boyfriend is the father of her 2-year-old son |
| 12:00 PM | Judge Mathis Former family members sue over harassing voicemails and vandalized vehicles |
| 1:00 PM | George Lopez Episode: George Doesn't Trustee Angie's Brother Angie's scam-artist brother, Ray (guest star Andy Garcia), reappears after a long absence, looking to make amends with his estranged daughter, Veronica, and the Lopez family |
| 1:30 PM | Seinfeld Episode: The Deal Jerry and Elaine (Jerry Seinfeld, Julia Louis-Dreyfus) come up with one stipulation when they discuss getting back together as a couple. With Jason Alexander |
| 2:00 PM | Friends Episode: The One With the Giant Poking Device Chandler and Janice (Matthew Perry, Maggie Wheeler) reach a turning point in their relationship; the Ugly Naked Guy may be dead |
| 2:30 PM | Friends Episode: The One With Ross' Step Forward Ross' new girlfriend wants to put their photograph on Christmas cards; Rachel eyes Joey as a possible romantic partner; the newlyweds cope with Chandler's boss as he goes through a divorce |
| 3:00 PM | Judge David Young Neighbors argue over a dogfight; a woman sues her younger sister for unpaid bills |
| 3:30 PM | Judge David Young A woman sues a salon owner for medical expenses for a nail infection; a man sues for the cost of a bus |
| 4:00 PM | Jerry Springer A woman admits to cheating on her man; longtime friends fight over a man |
| 5:00 PM | Maury Maury follows up with past guests and reveals the winner of the children's singing contest |
| 6:00 PM | The People's Court Judge Marilyn Milian adjudicates cases for people who have filed grievances in small-claims court |
| 7:00 PM | Two and a Half Men Episode: Smooth as a Ken Doll Charlie gets close to Herb's witty sister, as Judith and Herb's wedding nears |
| 7:30 PM | Two and a Half Men Episode: Madame and Her Special Friend A wealthy, elderly woman (guest star Cloris Leachman) sets her sights on Alan |
| 8:00 PM | American Idol The top 12 finalists reunite; the winner is announced |
| 10:00 PM | Eyewitness News at 10 All the news one hour earlier. It's FIRST on FOX! |
| 11:00 PM | Family Guy Episode: Breaking Out Is Hard to Do When Lois steals from the grocery store, she becomes addicted to the adrenaline rush and goes on a thieving spree that lands her in jail |
| 11:30 PM | The Simpsons Episode: Marge's Son Poisoning Realizing that Marge is lonely, Bart decides to spend extra time with her, causing his classmates to call him a mama's boy |